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IKBKB (IKK Beta) Recombinant Human Protein DFS Item

IKBKB (IKK Beta) Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3836

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Catalog No. PV3836



Description

Description

Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex.
Specifications

Specifications

NP_001547
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
114kDa
95% by SDS-PAGE
–80°C
1 Each
IKBKB (IKK beta)
IKBKB (IKK beta) was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 50μg/mL IKKtide peptide substrate (KKKKERLLDDRHDSGLDSMKDEE) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
IKK
63nmoles of phosphate transferred to IKKtide peptide substrate (KKKKERLLDDRHDSGLDSMKDEE) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL
GST Tag
0.4mg/mL
3551, 4088
IKBKB (IKK beta) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
IKBKB (IKK beta) Recombinant Human Protein
Kinase assay
Baculovirus
IKBKB (IKK beta) Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.