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Ikaros Mouse anti-Mouse, Clone: 2A9-mIkaros, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $421.08

Specifications

Antigen Ikaros
Clone 2A9-mIkaros
Host Species Murine
Gene Alias IZKF1
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50245565 Life Technologies
LS14578080
25μg Each for $170.28
50245566 Life Technologies
LS14578082
100μg Each for $421.08
Specifications

Description

This 2A9-mIkaros monoclonal antibody reacts with mouse Ikaros, the 70kDa founding member of the Ikaros family of C2H2-type zinc finger transcription factors. Ikaros is expressed in hematopoietic progenitor cells, thymocytes, mature T and B cells, monocytes, macrophages, and natural killer cells. This protein has also been shown to be expressed in non-immune cells such as neurons. Studies indicate that Ikaros can interact with other family members, namely Aiolos and Eos. Ikaros is involved in thymocyte development, B cell differentiation, cell cycle control, chromatin remodeling, and tumor suppression. Moreover, Ikaros has been implicated in leukemia and lymphoma. Ikaros has been demonstrated to regulate expression of Tdt, CD8a, and Notch target genes.

At least eight Ikaros isoforms exist due to alternative splicing. The 2A9-mIkaros antibody has been reported to recognize Ikaros isoform VI (Ik-6), which is the longest and most predominant.
Description & Specifications

Specifications

Ikaros
Murine
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
2A9-mIkaros
IZKF1
Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL