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Thermo Scientific™ IGF-1R (β -Subunit) Ab-5, Mouse Monoclonal Antibody


Ideal for a variety of molecular biology techniques, Thermo Scientific™ IGF-1R (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results. 

Manufacturer: thermo scientific™  MS645P1ABX

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Catalog No. MS645P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen IGF-1R (beta-Subunit) Ab-5
Applications Western Blotting
Classification Monoclonal
Clone 1-2
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Immunogen A 15-mer peptide corresponding to aa 1323-1337 (Tyr-RKNERALPLPQSSTC) from the C-terminal of Beta-subunit of human IGF-1R
Isotype IgG2b kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Neuroscience
Type Primary

Ideal for a variety of molecular biology techniques, Thermo Scientific™ IGF-1R (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results. 

IGF-1R consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.

Host Species: Mouse

Clone: 1-2

Isotype: IgG2b/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 1323-1337

Immunogen: A 15-mer peptide corresponding to aa 1323-1337 (Tyr-RKNERALPLPQSSTC) from the C-terminal of β-subunit of human IGF-1R

Molecular Weight: 95kDa

Positive Control: Placenta or Breast CA

Cellular Localization: Membrane Ab-5 is the antibody-of-choice for Western blotting of Beta-subunit of IGF-1R. Ab-3 reacts only weakly with hybrids of Insulin Receptor and IGF-1R while Ab-5 reacts very well. So, Ab-3, in conjunction with Ab-5, has proved useful in the isolation of hybrid receptors.

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Not optimum)
  • Affinity Purification of HYBRID and IGF-1R

Note:

USA: RUO; Int'l: RUO