Thermo Scientific™ IGF-1R (β -Subunit) Ab-5, Mouse Monoclonal Antibody
Ideal for a variety of molecular biology techniques, Thermo Scientific™ IGF-1R (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Thermo Scientific™ MS645P1ABX
Ideal for a variety of molecular biology techniques, Thermo Scientific™ IGF-1R (β-Subunit) Ab-5, Mouse Monoclonal Antibody provides accurate, reproducible results.IGF-1R consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
Host Species: Mouse
Species Reactivity: Human and Rat. Others not known.
Epitope: aa 1323-1337
Immunogen: A 15-mer peptide corresponding to aa 1323-1337 (Tyr-RKNERALPLPQSSTC) from the C-terminal of β-subunit of human IGF-1R
Molecular Weight: 95kDa
Positive Control: Placenta or Breast CA
Cellular Localization: Membrane Ab-5 is the antibody-of-choice for Western blotting of Beta-subunit of IGF-1R. Ab-3 reacts only weakly with hybrids of Insulin Receptor and IGF-1R while Ab-5 reacts very well. So, Ab-3, in conjunction with Ab-5, has proved useful in the isolation of hybrid receptors.
- Western Blotting
- Immunoprecipitation (Not optimum)
- Affinity Purification of HYBRID and IGF-1R
USA: RUO; Int'l: RUO
|IGF-1R (beta-Subunit) Ab-5|
|A 15-mer peptide corresponding to aa 1323-1337 (Tyr-RKNERALPLPQSSTC) from the C-terminal of Beta-subunit of human IGF-1R|