Thermo Scientific™ IGF-1 R (α -Subunit) Ab-2, Mouse Monoclonal Antibody
Recommended for Immunoprecipitation, Thermo Scientific™ IGF-1 R (α-Subunit) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Thermo Scientific™ MS642P1ABX
Recommended for Immunoprecipitation, Thermo Scientific™ IGF-1 R (α-Subunit) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
Host Species: Mouse
Species Reactivity: Human, Pig and Rabbit. Does not react with rat. Others not known.
Epitope: aa 514-586 (exon 7/8)
Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Molecular Weight: 125kDa
Positive Control: Placenta or Breast CA
Cellular Localization: Membrane Ab-2 is suitable for studies on pig and rabbit IGF-1R.
- Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA)
- Does Not Significantly Inhibit IGF Binding
USA: RUO; Int'l: RUO
|IGF-1R (alpha-Subunit) Ab-2|
|IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA|