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Thermo Scientific™ IGF-1 R (α -Subunit) Ab-2, Mouse Monoclonal Antibody

Recommended for Immunoprecipitation, Thermo Scientific™ IGF-1 R (α-Subunit) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer:  Thermo Scientific™ MS642P1ABX

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Catalog No. MS642P1ABX


 

Specifications

Description

Recommended for Immunoprecipitation, Thermo Scientific™ IGF-1 R (α-Subunit) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.

Host Species: Mouse

Clone: 17-69

Isotype: IgG1

Species Reactivity: Human, Pig and Rabbit. Does not react with rat. Others not known.

Epitope: aa 514-586 (exon 7/8)

Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Molecular Weight: 125kDa

Positive Control: Placenta or Breast CA

Cellular Localization: Membrane Ab-2 is suitable for studies on pig and rabbit IGF-1R.

Recommended for:

  • Immunoprecipitation
  • Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA)
  • Does Not Significantly Inhibit IGF Binding

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

IGF-1R (alpha-Subunit) Ab-2
17-69
Unlabeled
Murine
IgG1
RUO
Primary
Human,Porcine,Rabbit
Monoclonal
1mg/mL
Concentrated
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
100μL
Neuroscience
Monoclonal