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Thermo Scientific™ IGF-1 R (α -Subunit) Ab-2, Mouse Monoclonal Antibody


Recommended for Immunoprecipitation, Thermo Scientific™ IGF-1 R (α-Subunit) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™  MS642P1ABX

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Catalog No. MS642P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen IGF-1R (alpha-Subunit) Ab-2
Classification Monoclonal
Clone 17-69
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Porcine
Cross Reactivity Rabbit
Format Concentrated
Host Species Murine
Immunogen IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline Neuroscience
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Porcine
Target Species Rabbit

Recommended for Immunoprecipitation, Thermo Scientific™ IGF-1 R (α-Subunit) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.

Host Species: Mouse

Clone: 17-69

Isotype: IgG1

Species Reactivity: Human, Pig and Rabbit. Does not react with rat. Others not known.

Epitope: aa 514-586 (exon 7/8)

Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Molecular Weight: 125kDa

Positive Control: Placenta or Breast CA

Cellular Localization: Membrane Ab-2 is suitable for studies on pig and rabbit IGF-1R.

Recommended for:

  • Immunoprecipitation
  • Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA)
  • Does Not Significantly Inhibit IGF Binding

Note:

USA: RUO; Int'l: RUO