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IDO Mouse anti-Human, Clone: V1NC3IDO, eBioscience™

Mouse Monoclonal Antibody

$114.55 - $288.55

Specifications

Antigen IDO
Clone V1NC3IDO
Host Species Mouse
Gene Alias Indoleamine-2,3-dioxygenase
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122819

 
affymetrix
14975080
25μg Each for $114.55

501122820

 
affymetrix
14975082
100μg Each for $288.55
Description & Specifications

Specifications

Antigen IDO
Clone V1NC3IDO
Host Species Mouse
Gene Alias Indoleamine-2,3-dioxygenase
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody V1NC3IDO recognizes human IDO. IDO (indoleamine-2,3-dioxygenase, INDO, IDO1) is an intracellular enzyme that catalyzes the degradation of tryptophan to kynurenines. IDO is expressed in a wide variety of tissues and cells, including macrophages, plasmacytoid dendritic cells, and several cell lines. IDO can be induced in many different cell types by IFN gamma or other inflammatory stimuli. Expression of IDO in antigen presenting cells and tumors is thought to mediate immune suppression through depletion of this essential amino acid and/or by the creation of tryptophan metabolites that cause apoptosis of T cells and induction of regulatory T cells.

This V1NC3IDO antibody reacts with IDO1 and does not cross react with IDO2.