Please login to your online account to display your discounted pricing

I kappa B zeta Rat anti-Mouse, PerCP-eFluor 710, Clone: LK2NAP, eBioscience™

Rat Monoclonal Antibody

$187.05 - $477.05

Specifications

Antigen I kappa B zeta
Clone LK2NAP
Host Species Rat
Gene Alias IKBZ, INAP, MAIL, NF-kappa-B inhibitor zeta, Nfkbiz
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123881

 
affymetrix
46680180
25μg Each for $187.05

501123882

 
affymetrix
46680182
100μg Each for $477.05
Description & Specifications

Specifications

Antigen I kappa B zeta
Clone LK2NAP
Host Species Rat
Gene Alias IKBZ, INAP, MAIL, NF-kappa-B inhibitor zeta, Nfkbiz
Species Reactivity Mouse
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The LK2NAP monoclonal antibody reacts with mouse IkB zeta (INAP, MAIL). IkBz is a member of the IkB family of cytoplasmic proteins and transcription factors and also shares structural homology with Bcl-3. It is induced in monocytes, macrophages and B cells in response to TLR and IL-1R signaling. In NK cells, IkBz is rapidly upregulated in response to IL-12 and IL-18 and is necessary for production of IFN gamma. In T cells, IkBz is not necessary for IFN gamma and IL-4 production by Th1 and Th2 cells, respectively. However in Th17 cells, IkBz acts in concert with RORa and RORgt to upregulate IL-17A, IL-17F, IL-21, IL-22 and IL-23R expression.