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I kappa B zeta Rat anti-Mouse, Clone: LK2NAP, eBioscience™

Rat Monoclonal Antibody

$130.68 - $328.68

Specifications

Antigen I kappa B zeta
Clone LK2NAP
Host Species Rat
Gene Alias NF-kappa-B inhibitor zeta, Nfkbiz
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122719 Life Technologies
LS14680180
25μg Each for $130.68
501122720 Life Technologies
LS14680182
100μg Each for $328.68
Specifications

Description

The LK2NAP monoclonal antibody reacts with mouse IkB zeta (INAP, MAIL). IkBz is a member of the IkB family of cytoplasmic proteins and transcription factors and also shares structural homology with Bcl-3. It is induced in monocytes, macrophages and B cells in response to TLR and IL-1R signaling. In NK cells, IkBz is rapidly upregulated in response to IL-12 and IL-18 and is necessary for production of IFN gamma. In T cells, IkBz is not necessary for IFN gamma and IL-4 production by Th1 and Th2 cells, respectively. However in Th17 cells, IkBz acts in concert with RORa and RORgt to upregulate IL-17A, IL-17F, IL-21, IL-22 and IL-23R expression.
Description & Specifications

Specifications

I kappa B zeta
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
LK2NAP
NF-kappa-B inhibitor zeta, Nfkbiz
Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL