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I kappa B zeta Rat anti-Mouse, Clone: LK2NAP, eBioscience™

Rat Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen I kappa B zeta
Clone LK2NAP
Host Species Rat
Gene Alias NF-kappa-B inhibitor zeta, Nfkbiz
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122719

 
affymetrix
14680180
25μg Each for $143.55

501122720

 
affymetrix
14680182
100μg Each for $361.05
Description & Specifications

Specifications

Antigen I kappa B zeta
Clone LK2NAP
Host Species Rat
Gene Alias NF-kappa-B inhibitor zeta, Nfkbiz
Species Reactivity Mouse
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The LK2NAP monoclonal antibody reacts with mouse IkB zeta (INAP, MAIL). IkBz is a member of the IkB family of cytoplasmic proteins and transcription factors and also shares structural homology with Bcl-3. It is induced in monocytes, macrophages and B cells in response to TLR and IL-1R signaling. In NK cells, IkBz is rapidly upregulated in response to IL-12 and IL-18 and is necessary for production of IFN gamma. In T cells, IkBz is not necessary for IFN gamma and IL-4 production by Th1 and Th2 cells, respectively. However in Th17 cells, IkBz acts in concert with RORa and RORgt to upregulate IL-17A, IL-17F, IL-21, IL-22 and IL-23R expression.