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Hydroxyurea, 98%, Alfa Aesar™

$401.73 - $401.73

Chemical Identifiers

Chemical Name or Material Hydroxyurea
CAS 127-07-1
Molecular Formula CH4N2O2
Formula Weight 76.06g/mol
MDL Number MFCD00007943
Beilstein 1741548
Merck Index 14,4848
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Products
Catalog Number Mfr. No. Packaging Quantity Price Quantity    

AAA1083114

 
alfa aesar
A10831-14
Each for $401.73
Description & Specifications

Specifications

Melting Point ≈140°C (dec.)
Quantity 25g
Chemical Name or Material Hydroxyurea
CAS 127-07-1
Assay 98%
Molecular Formula CH4N2O2
Formula Weight 76.06g/mol
MDL Number MFCD00007943
Beilstein 1741548
Merck Index 14,4848
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H340-H360;
May cause genetic defects.
May damage fertility or the unborn child.
Health Hazard 3 GHS P Statement
P281-P201-P202-P308+P313-P405-P501a;
Use personal protective equipment as required.
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
IF exposed or concerned: Get medical advice/attention.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
RTECS Number YT4900000

Applications
Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.

Solubility
Soluble in water, hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.

Notes
Moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Safety and Handling

Danger

GHS P Statement
P281-P201-P202-P308+P313-P405-P501a;
Use personal protective equipment as required.
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
IF exposed or concerned: Get medical advice/attention.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H340-H360;
May cause genetic defects.
May damage fertility or the unborn child.