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eBioscience™ Human TPO, Recombinant Protein, Carrier-Free

Human Recombinant Protein

$143.55 - $317.55

Specifications

Name TPO
Recombinant Yes
Conjugate Unlabeled
Purity >98%
Purification Method SDS-PAGE and HPLC
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123512

 
ebioscience™
34868561
2μg Each for $143.55

501123513

 
ebioscience™
34868563
10μg Each for $317.55
Description & Specifications

Specifications

Name TPO
Recombinant Yes
Conjugate Unlabeled
Purity >98%
Purification Method SDS-PAGE and HPLC
Source E. coli
For Use With (Application) Functional Assays
Molecular Weight 18.6kDa
Storage Requirements Store lyophilized protein at less than or equal to -20°C. Reconstituted protein solution can be stored with carrier-protein (e.g., 0.1% BSA) at less than or equal to -20°C.

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.