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Human sVEGF R1/Flt-1 Quantikine ELISA Kit, R&D Systems


Manufacturer: r & d systems  RDSDVR100B

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Catalog No. DVR100B

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Description & Specifications

Specifications

Gene ID (Entrez) 2321
Packaging Quantity 1 Plate
Quantity 1 Kit
Sample Type Cell Culture Supernates, Serum, EDTA Plasma, Saliva, Follicular Fluid
Sample Volume Cell Culture Supernates (100μL), Serum (100μL), EDTA Plasma (100μL), Saliva (100μL), Follicular Fluid (100μL)
Species Human

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Assay Type: Solid Phase Sandwich ELISA
Sample Type/Volume Required: Cell Culture Supernates (100μL), Serum (100μL), EDTA Plasma (100μL), Saliva (100μL), Follicular Fluid (100μL)
Sensitivity: 13.3pg/mL
Specificity: Natural and recombinant human soluble VEGF R1
Cross Reactivity: <50% cross-species reactivity observed with species tested. <0.5% cross-reactivity observed with available related molecules.