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Thermo Scientific™ Lab Vision™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1653P1ABX

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Catalog No. MS1653P1ABX

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Description & Specifications

Specifications

Antigen Human Sodium Iodide Symporter (hNIS) Ab-1
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone FP5A
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen A synthetic peptide corresponding to aa625-643 of hNIS protein
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody.

Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid. Antibody to NIS showed strong immunostaining in Graves tissues, intermediate staining in papillary and follicular thyroid cancer, and no staining in Hurtle cell cancer or in nonthyroidal tissue.

Host Species: Mouse

Clone: FP5A

Isotype: IgG1/κ

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: aa 625-643

Immunogen: A synthetic peptide corresponding to aa 625-643 of hNIS protein

Molecular Weight: 97kDa

Positive Control: Thyroid

Cellular Localization: Membrane and cytoplasm

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Not verified)

Note:

USA: RUO; Int'l: RUO