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Thermo Scientific™ Lab Vision™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS1653P1ABX

 View more versions of this product

Catalog No. MS1653P1ABX


 

Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody.

Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid. Antibody to NIS showed strong immunostaining in Graves tissues, intermediate staining in papillary and follicular thyroid cancer, and no staining in Hurtle cell cancer or in nonthyroidal tissue.

Host Species: Mouse

Clone: FP5A

Isotype: IgG1/κ

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: aa 625-643

Immunogen: A synthetic peptide corresponding to aa 625-643 of hNIS protein

Molecular Weight: 97kDa

Positive Control: Thyroid

Cellular Localization: Membrane and cytoplasm

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Not verified)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Human Sodium Iodide Symporter (hNIS) Ab-1
Monoclonal
1mg/mL
Human
Ab without BSA/Azide (Frozen)
A synthetic peptide corresponding to aa625-643 of hNIS protein
100μL
Primary
Human
Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting
FP5A
Unlabeled
Concentrated
Murine
IgG2a kappa
RUO
Monoclonal