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Invitrogen™ Human PILR-alpha ELISA Kit
Human PILR-alpha quantitates human PILR-alpha in serum, plasma, supernatant.
$796.00 - $3950.00
Specifications
Accession Number | AV021745; Cell surface receptor FDF03; FDF03; Inhibitory receptor PILR-alpha; paired immunoglobin like type 2 receptor alpha; paired immunoglobin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha; Pilra |
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Assay Range | 5.5 to 1,500 pg/mL |
Assay Sensitivity | 5.5 pg/mL |
Conjugate | Biotin |
Product Type | ELISA |
Description
Human PILR-alpha quantitates human PILR-alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PILR-alpha.
SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILR beta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILR alpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Specifications
AV021745; Cell surface receptor FDF03; FDF03; Inhibitory receptor PILR-alpha; paired immunoglobin like type 2 receptor alpha; paired immunoglobin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha; Pilra | |
5.5 pg/mL | |
ELISA | |
Colorimetric Microplate Reader | |
PILRA | |
<10% | |
HRP | |
Supernatant, 50 μL; Serum, 50 μL; Plasma, 50 μL | |
PILRA | |
4 hr 45 min |
5.5 to 1,500 pg/mL | |
Biotin | |
Plasma, Serum, Supernatant | |
Q9UKJ1 | |
<12% | |
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
Research Use Only | |
2°C to 8°C | |
1 hr 20 min |