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Invitrogen™ Human PILR-alpha ELISA Kit DFS Item

Human PILR-alpha quantitates human PILR-alpha in serum, plasma, supernatant.

$796.00 - $3950.00

Specifications

Accession Number AV021745; Cell surface receptor FDF03; FDF03; Inhibitory receptor PILR-alpha; paired immunoglobin like type 2 receptor alpha; paired immunoglobin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha; Pilra
Assay Range 5.5 to 1,500 pg/mL
Assay Sensitivity 5.5 pg/mL
Conjugate Biotin
Product Type ELISA
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Description

Description

Human PILR-alpha quantitates human PILR-alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PILR-alpha.

SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILR beta-mediated activation. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILR alpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.
Specifications

Specifications

AV021745; Cell surface receptor FDF03; FDF03; Inhibitory receptor PILR-alpha; paired immunoglobin like type 2 receptor alpha; paired immunoglobin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha; Pilra
5.5 pg/mL
ELISA
Colorimetric Microplate Reader
PILRA
<10%
HRP
Supernatant, 50 μL; Serum, 50 μL; Plasma, 50 μL
PILRA
4 hr 45 min
5.5 to 1,500 pg/mL
Biotin
Plasma, Serum, Supernatant
Q9UKJ1
<12%
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Research Use Only
2°C to 8°C
1 hr 20 min
Videos
SDS
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