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Invitrogen™ eBioscience™ Human PD-L2 Platinum ELISA Kit

For quantitative detection of human PD-L2.

Manufacturer:  Invitrogen™ LSBMS2215

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Catalog No. 501125372



Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human PD-L2

Description

Description

CD273 (PDCD1 Ligand 2, Programmed cell death 2 ligand 2, PD-L2, B7-DC) is involved in cell-mediated immune responses initiated by T lymphocytes that are stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as CD273 that mediate inhibitory signals from the APC (antigen presenting cell). CD273 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; CD273 is specific to the largest isoform. Diseases associated with CD273 include cysticercosis, and myasthenic syndrome.
Specifications

Specifications

Q9BQ51
Biotin
80380
Pre-coated 96 well plate, Adhesive Plate Covers, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Controls
96 tests
3.65 pg/mL
10μL
Human
1 hr 20 min
Human
PDCD1LG2, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2
4.5%
39-2,500 pg/mL
ELISA
Colorimetric Microplate Reader
ELISA
RUO
Cell Lysates, Plasma, Serum, Supernatants
Cell Lysates (10μL), Plasma (10μL), Serum (10μL), Supernatants (10μL)
2-8°C
3 hr 30 min
PDCD1LG2
3.1%
HRP
Documents