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Invitrogen™ Human NOR-1 (aa 377-455) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant.
Specifications
Specifications
| Accession Number | Q92570 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 8013 |
| Name | Human NOR-1 (aa 377-455) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | AI573420; CHN; chondrosarcoma, extraskeletal myxoid, fused to EWS; CSMF; MINOR; mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; neuron-derived orphan receptor 1/2; Nor1; NOR-1; NOR-2; Nr4a3; Nuclear hormone receptor NOR-1; nuclear hormone receptor NOR-1/NOR-2; Nuclear receptor subfamily 4 group A member 3; nuclear receptor subfamily 4, group A, member 3; Orphan nuclear receptor TEC; TEC; TEC receptor; Translocated in extraskeletal chondrosarcoma |
| Common Name | NOR-1 |
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