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eBioscience™ Human IL-6, Recombinant Protein

Human Recombinant Protein

$158.05 - $375.55

Specifications

Structural Form E. coli expressed amino acids Pro 29-Met 212 of mature human IL-6 accession # AF372214
Purity >98%
Purification Method SDS-PAGE
Molecular Weight The methionylated N-terminal protein has a predicted molecular mass of 21,041. The DTT-reduced and non-reduced protein migrate as 16kDa polypeptides on SDS-PAGE.
Source E. coli
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501128757

 
ebioscience™
14-8069-80
25μg Each for $375.55

501128815

 
ebioscience™
14-8069-62
5μg Each for $158.05
Description & Specifications

Specifications

Structural Form E. coli expressed amino acids Pro 29-Met 212 of mature human IL-6 accession # AF372214
Purity >98%
Purification Method SDS-PAGE
Molecular Weight The methionylated N-terminal protein has a predicted molecular mass of 21,041. The DTT-reduced and non-reduced protein migrate as 16kDa polypeptides on SDS-PAGE.
Source E. coli
Accession Number AF372214
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Formulation Sterile liquid; 10mM sodium phosphate, pH 7.2, 150mM NaCl, 0.5% BSA. 0.22μm filtered.
Biological Activity Measured by human TF-1 cell proliferation assay. The ED50 is 0.1ng/mL, corresponding to a specific activity of 1.0 x 107 Units/mg.
For Use With (Application) Cytokine Bioassays
Validated Application FA
Conjugate Unlabeled
Regulatory Status RUO
Cross Reactivity Human
Gene Symbol Interleukin-6, IL6
Name IL-6
Recombinant Yes

Human IL-6 (also known as B Cell Stimulating Factor BCSF, BSF-2) is a ∽21-28 kDa factor produced by a variety of cell types including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. This pleiotrophic cytokine influences antigen-specific immune response, inflammatory response, and the development of neurons and is a major mediator of the acute phase reaction.