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eBioscience™ Human IL-34, Recombinant Protein, Carrier-Free

Human Recombinant Protein

$143.55 - $317.55

Specifications

Name IL-34
Recombinant Yes
Conjugate Unlabeled
Purity >95%
Purification Method SDS-PAGE and HPLC
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123510

 
ebioscience™
34868461
2μg Each for $143.55

501123511

 
ebioscience™
34868463
10μg Each for $317.55
Description & Specifications

Specifications

Name IL-34
Recombinant Yes
Conjugate Unlabeled
Purity >95%
Purification Method SDS-PAGE and HPLC
Source HEK 293 cells
For Use With (Application) Functional Assays
Molecular Weight 52.5kDa
Storage Requirements Store lyophilized protein at less than or equal to -20°C. Reconstituted protein solution can be stored with carrier protein (e.g., 0.1% BSA) at less than or equal to -20°C.

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.