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eBioscience™ Human IL-2, Recombinant Protein

Human Recombinant Protein

$245.05 - $752.55

Specifications

Structural Form E. coli
Purity >98%
Purification Method SDS-PAGE
Molecular Weight 15kDa
Source E. coli
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501128755

 
ebioscience™
14-8029-81
50μg Each for $752.55

501129054

 
ebioscience™
14-8029-63
10μg Each for $245.05
Description & Specifications

Specifications

Structural Form E. coli
Purity >98%
Purification Method SDS-PAGE
Molecular Weight 15kDa
Source E. coli
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Formulation Sterile liquid: 40mM Acetate, 0.2M NaCl, pH 5, 1.0% BSA . 0.22μm filtered.
Biological Activity The ED50 of this protein, as measured by CTLL-2 proliferation assay, is less than or equal to 175pg/mL. This corresponds to a specific activity of greater than or equal to 5.7 x 106 Units/mg.
For Use With (Application) Cytokine Bioassays
Validated Application FA
Conjugate Unlabeled
Regulatory Status RUO
Cross Reactivity Human
Gene Symbol Interleukin-2
Name IL-2
Recombinant Yes

Human IL-2 (also known as TCGF) is a ∽15 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.