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eBioscience™ Human IFN beta, Recombinant Protein, Carrier-Free

Human Recombinant Protein

$346.55 - $1,260.05

Specifications

Structural Form CHO cells (amino acids Met22-Asn187; Accession # AAC41702.1)
Purity >95%
Purification Method SDS-PAGE and HPLC
Molecular Weight 20kDa
Source CHO Cells
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123521 Life Technologies
LS34869982
100μg Each for $1,260.05
501129116 Life Technologies
LS34869964
20μg Each for $346.55
Specifications

Description

Human interferon beta is a glycosylated member of the type I family of interferons, which also includes IFN alpha. Human IFN alpha and beta share 50% amino acid sequence homology and bind the IFN a/b receptor (IFNAR), which consists of two subunits IFNAR1 and IFNAR2, with different affinities. Binding of IFN to its receptor activates signal transduction, including the JAK/STAT and p38 MAPK pathways. Many studies have established IFN beta as a mediator of anti-viral, anti-proliferative, and anti-inflammatory functions, as well as an effective treatment for multiple sclerosis.
Description & Specifications

Specifications

CHO cells (amino acids Met22-Asn187; Accession # AAC41702.1)
SDS-PAGE and HPLC
CHO Cells
Lyophilized from 10mM sodium citrate, 100mM sodium chloride, and 10mM sucrose
Functional Assays
RUO
IFN beta
>95%
20kDa
Less than 0.1ng/μg cytokine as determined by the LAL assay
The ED50 of this protein, as measured by stimulation of human TF-1 cell proliferation, is less than or equal to 0.1ng/mL, which corresponds to a specific activity of at least 1 x 107 units/mg.
Unlabeled
Human
Yes