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eBioscience™ Human CD257 (BAFF, BLyS), Recombinant Protein

Human Recombinant Protein

$143.88 - $315.48


Name CD257 (BAFF, BLyS)
Recombinant Yes
Conjugate Unlabeled
Purity >90%
Purification Method reducing SDS-PAGE
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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5018543 Life Technologies
5μg Each for $143.88
5018544 Life Technologies
25μg Each for $315.48


Recombinant human BAFF (B-cell activating factor), also referred to as BlyS, is a type II transmembrane protein of the TNF superfamily. BAFF is found on T cells, macrophages and dendritic cells. BAFF contains a cytoplasmic domain, transmembrane domain and extracellular domain which can be cleaved between amino acid 133 and 134 to produce a soluble form detectable in serum. Receptors for BAFF include TACI, BAMBI and BAFFR. BAFF/BLyS is a B lymphocyte stimulatory molecule; it induces B cell proliferation and immunoglobulin secretion. In addition BAFF can provide a co-stimulation signal to T lymphocytes. Elevated levels of BAFF has been implicated in the pathogenesis of some autoimmune diseases (particularly) B cell diseases such as systemic lupus erythaematosus. Human and mouse BAFF share 86% amino acid sequence identity.
Description & Specifications


CD257 (BAFF, BLyS)
reducing SDS-PAGE
Cytokine Bioassays
Store at less than or equal to -70°C.
E. coli