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eBioscience™ Human CD257 (BAFF, BLyS), Recombinant Protein

Human Recombinant Protein

$158.05 - $346.55

Specifications

Name CD257 (BAFF, BLyS)
Recombinant Yes
Conjugate Unlabeled
Purity >90%
Purification Method reducing SDS-PAGE
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Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5018543 Life Technologies
LS14894362
5μg Each for $158.05
5018544 Life Technologies
LS14894380
25μg Each for $346.55
Specifications

Description

Recombinant human BAFF (B-cell activating factor), also referred to as BlyS, is a type II transmembrane protein of the TNF superfamily. BAFF is found on T cells, macrophages and dendritic cells. BAFF contains a cytoplasmic domain, transmembrane domain and extracellular domain which can be cleaved between amino acid 133 and 134 to produce a soluble form detectable in serum. Receptors for BAFF include TACI, BAMBI and BAFFR. BAFF/BLyS is a B lymphocyte stimulatory molecule; it induces B cell proliferation and immunoglobulin secretion. In addition BAFF can provide a co-stimulation signal to T lymphocytes. Elevated levels of BAFF has been implicated in the pathogenesis of some autoimmune diseases (particularly) B cell diseases such as systemic lupus erythaematosus. Human and mouse BAFF share 86% amino acid sequence identity.
Description & Specifications

Specifications

CD257 (BAFF, BLyS)
Unlabeled
reducing SDS-PAGE
Cytokine Bioassays
Store at less than or equal to -70°C.
Yes
>90%
E. coli
18.5kDa