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eBioscience™ Human Activin A, Recombinant Protein

Human Recombinant Protein

$230.55 - $680.05

Specifications

Name Activin A
Recombinant Yes
Conjugate Unlabeled
Purity ≥95%
Purification Method SDS-PAGE
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

5018570

 
ebioscience™
14-8993-62
5μg Each for $230.55

5018571

 
ebioscience™
14899380
25μg Each for $680.05
Description & Specifications

Specifications

Name Activin A
Recombinant Yes
Conjugate Unlabeled
Purity ≥95%
Purification Method SDS-PAGE
Source Insect Cells
For Use With (Application) Cytokine Bioassays
Molecular Weight 26kDa
Storage Requirements Store at less than or equal to -70°C.

Activin A is a member of the TGF-β superfamily, along with the other activin proteins and the structurally related inhibins. The activins are dimeric proteins formed by the association of two of the four existing β subunits, βA, βB, βC, and βE. These subunits are shared with the inhibin proteins, which are heterodimers of one β and one α chain. Activin A is a homodimer of two 13 kDa βA subunits, which can also associate with βB or βC to form Activin AB or AC, respectively. Activin A is expressed by various cell types and exhibits pleiotropic effects including the regulation of metabolism, homeostasis, cell proliferation and differentiation, apoptosis, and tissue healing. Activin A has been recently reported to work in synergy with TGF-β to promote the induction of antigen specific iTreg cells leading to inhibition of Th1 and Th2-mediated responses.