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Thermo Scientific™ Lab Vision™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-4, Mouse Monoclonal Antibody

Recommended for Immunohistochemistry (Formalin/paraffin), Thermo Scientific™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

$726.18 - $1,347.88

Specifications

Antigen HIF-1alpha (Hypoxia-Inducible Factor-1alpha) Ab-4
Clone H1alpha67
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
View More Specs
Products
Catalog Number Mfr. No. Concentration Quantity Price Quantity    

MS1164P

 
thermo scientific™ lab vision™
MS-1164-P
200�g/mL 1mL Each for $1,212.33

MS1164P1

 
thermo scientific™ lab vision™
MS-1164-P1
200�g/mL 500µL Each for $726.18

MS1164P1ABX

 
thermo scientific™ lab vision™
MS1164P1ABX
1mg/mL 100µL Each for $810.90

MS1164PABX

 
thermo scientific™ lab vision™
MS1164PABX
1mg/mL 200µL Each for $1,347.88
Description & Specifications

Specifications

Antigen HIF-1alpha (Hypoxia-Inducible Factor-1alpha) Ab-4
Clone H1alpha67
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Ferret
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Sheep
Cross Reactivity Ferret
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Sheep
Cross Reactivity Ferret
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Sheep
Cross Reactivity Ferret
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Sheep
Cross Reactivity Ferret
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Sheep
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline Transcription Regulation
Type Primary
Immunogen Recombinant hHIF-1alpha (aa 432-528) protein
Isotype IgG2b kappa

Recommended for Immunohistochemistry (Formalin/paraffin), Thermo Scientific™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

HIF-1 (hypoxia-inducible factor-1) is a heterodimer consisting of an alpha and a β subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors. HIF-1 is a key component of a widely operative transcriptional response activated by hypoxia, cobaltous ions, and iron chelation. HIF-1 activates transcription of hypoxia-inducible genes, including those encoding: erythropoietin, vascular endothelial growth (VEGF), heme oxygenase-1, inducible nitric oxide synthase, and the glycolytic enzymes aldolase A, enolase 1, lactate dehydrogenase A, phosphofructokinase I, and phosphoglycerate kinase 1. The C-terminal of HIF-1 alpha binds to p300. p300/CBP-HIF complexes participate in the induction of hypoxia-responsive genes, including VEGF.

Host Species: Mouse

Clone: H1α67

Isotype: IgG2b/κ

Species Reactivity: Human, Sheep, Mouse, Rat and Ferret. Others not known.

Epitope: aa 432-528

Immunogen: Recombinant hHIF-1α (aa 432-528) protein

Molecular Weight: 120kDa

Positive Control: Mammalian cells cultured under reduced O2 tension

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Immunoprecipitation (Not verified)

Note:

USA: RUO; Int'l: RUO