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Thermo Scientific™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-1, Mouse Monoclonal Antibody

Recommended for Immunofluorescence and Gel Supershift, Thermo Scientific™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

$227.12 - $1,144.76

Specifications

Antigen HIF-1alpha (Hypoxia-Inducible Factor-1alpha) Ab-1
Clone OZ12
Applications Flow Cytometry
Applications Immunofluorescence
Applications Western Blotting
View More Specs
Products
Catalog Number Mfr. No. Concentration Quantity Price Quantity    

MS701P

 
thermo scientific™
MS-701-P
200�g/mL 1mL Each for $1,042.31

MS701P0

 
thermo scientific™
MS-701-P0
200�g/mL 100µL Each for $227.12

MS701P1

 
thermo scientific™
MS-701-P1
200�g/mL 500µL Each for $684.12

MS701P1ABX

 
thermo scientific™
MS701P1ABX
1mg/mL 100µL Each for $760.96

MS701PABX

 
thermo scientific™
MS-701-PABX
1mg/mL 200µL Each for $1,144.76
Description & Specifications

Specifications

Antigen HIF-1alpha (Hypoxia-Inducible Factor-1alpha) Ab-1
Clone OZ12
Applications Flow Cytometry
Applications Immunofluorescence
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Western Blotting
Applications Flow Cytometry
Applications Immunofluorescence
Applications Western Blotting
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline Stress Response
Type Primary
Immunogen hHIF-1alpha (aa 530-826) protein
Isotype IgG2a kappa

Recommended for Immunofluorescence and Gel Supershift, Thermo Scientific™ HIF-1α (Hypoxia-Inducible Factor-1α) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

HIF-1 (hypoxia-inducible factor-1) is a heterodimer consisting of an alpha and a β subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors. HIF-1 is a key component of a widely operative transcriptional response activated by hypoxia, cobaltous ions, and iron chelation. HIF-1 activates transcription of hypoxia-inducible genes, including those encoding: erythropoietin, vascular endothelial growth (VEGF), heme oxygenase-1, inducible nitric oxide synthase, and the glycolytic enzymes aldolase A, enolase 1, lactate dehydrogenase A, phosphofructokinase I, and phosphoglycerate kinase 1. The C-terminal of HIF-1 alpha binds to p300. p300/CBP-HIF complexes participate in the induction of hypoxia-responsive genes, including VEGF.

Host Species: Mouse

Clone: OZ12

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: aa 530-826

Immunogen: hHIF-1α (aa 530-826) protein

Molecular Weight: 120kDa

Positive Control: Mammalian cells cultured under reduced O2 tension

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO