Thermo Scientific™ Lab Vision™ HER-4/c-erbB-4 Ab-2, Rabbit Polyclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ HER-4/c-erbB-4 Ab-2, Rabbit Polyclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ RB284P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ HER-4/c-erbB-4 Ab-2, Rabbit Polyclonal Antibody.c-erbB-4 is the fourth member of class I receptor kinase family (ErbB). HER-4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum. Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDA-MB-330 and MDA-MB-361. Expression of erbB-4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
Host Species: Rabbit
Species Reactivity: Human, Rat and Mouse. Others not tested.
Epitope: aa 1285-1308
Immunogen: A synthetic peptide (aa 1285-1308) from the C-terminus of human HER-4/c-erbB-4 oncoprotein
Molecular Weight: 185kDa
Positive Control: T47D or MDA-MB-453 cells
Cellular Localization: Cytoplasmic and membrane
- Western Blotting (Not verified)
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|A synthetic peptide (aa 1285-1308) from the C-terminus of human c-erbB-4/HER-4 oncoprotein|