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Thermo Scientific™ Lab Vision™ HER-4/c-erbB-4 Ab-2, Rabbit Polyclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ HER-4/c-erbB-4 Ab-2, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB284P1ABX

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Catalog No. RB284P1ABX

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Description & Specifications

Specifications

Antigen HER-4/c-erbB-4 Ab-2
Applications Western Blotting
Classification Polyclonal
Clone Polyclonal
Concentration 1mg/mL
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide (aa 1285-1308) from the C-terminus of human c-erbB-4/HER-4 oncoprotein
Isotype IgG
Quantity 500µL
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ HER-4/c-erbB-4 Ab-2, Rabbit Polyclonal Antibody.

c-erbB-4 is the fourth member of class I receptor kinase family (ErbB). HER-4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum. Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDA-MB-330 and MDA-MB-361. Expression of erbB-4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Rat and Mouse. Others not tested.

Epitope: aa 1285-1308

Immunogen: A synthetic peptide (aa 1285-1308) from the C-terminus of human HER-4/c-erbB-4 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D or MDA-MB-453 cells

Cellular Localization: Cytoplasmic and membrane

Recommended for:

  • Western Blotting (Not verified)

Note:

USA: RUO; Int'l: RUO