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Thermo Scientific™ Lab Vision™ HER-4/c-erbB-4 Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Mouse Monoclonal Antibody with the Thermo Scientific™ HER-4/c-erbB-4 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS270P1ABX

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Catalog No. MS270P1ABX

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Description & Specifications

Specifications

Antigen HER-4/c-erbB-4 Ab-1
Applications Flow Cytometry
Applications Immunoprecipitation
Classification Monoclonal
Clone H4.77.16 (Ab77)
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Murine
Immunogen Extracellular fragment of recombinant human c-erbB-4/HER-4 oncoprotein
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine
Target Species Rat

Provide accurate, reproducible results with the Mouse Monoclonal Antibody with the Thermo Scientific™ HER-4/c-erbB-4 Ab-1, Mouse Monoclonal Antibody.

c-erbB-4 is the fourth member of class I receptor kinase family (ErbB). Down regulation of ErbB-4 in estrogen receptor-positive cancer cells inhibits proliferation.

Host Species: Mouse

Clone: H4.77.16; same as Ab77

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Extracellular fragment of recombinant human HER-4/c-erbB-4 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D or MDA-MB-453 cells

Cellular Localization: Membrane and cytoplasmic

Recommended for:

  • Western Blotting (Not suitable)
  • Immunoprecipitation
  • Flow Cytometry
  • Accelerates Internalization of HER-1
  • Stimulates Tyrosine Kinase Activity

Note:

USA: RUO; Int'l: RUO