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Thermo Scientific™ Lab Vision™ HER-4/c-erbB-4 Ab-1, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Mouse Monoclonal Antibody with the Thermo Scientific™ HER-4/c-erbB-4 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS270P1ABX

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Catalog No. MS270P1ABX

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Description & Specifications

Specifications

Antigen HER-4/c-erbB-4 Ab-1
Applications Flow Cytometry
Applications Immunoprecipitation
Classification Monoclonal
Clone H4.77.16 (Ab77)
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Immunogen Extracellular fragment of recombinant human c-erbB-4/HER-4 oncoprotein
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary

Provide accurate, reproducible results with the Mouse Monoclonal Antibody with the Thermo Scientific™ HER-4/c-erbB-4 Ab-1, Mouse Monoclonal Antibody.

c-erbB-4 is the fourth member of class I receptor kinase family (ErbB). Down regulation of ErbB-4 in estrogen receptor-positive cancer cells inhibits proliferation.

Host Species: Mouse

Clone: H4.77.16; same as Ab77

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Extracellular fragment of recombinant human HER-4/c-erbB-4 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D or MDA-MB-453 cells

Cellular Localization: Membrane and cytoplasmic

Recommended for:

  • Western Blotting (Not suitable)
  • Immunoprecipitation
  • Flow Cytometry
  • Accelerates Internalization of HER-1
  • Stimulates Tyrosine Kinase Activity

Note:

USA: RUO; Int'l: RUO