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Thermo Scientific™ Lab Vision™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS303P1ABX

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Catalog No. MS303P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen HER-3/c-erbB-3 Ab-5
Applications Immunofluorescence
Applications Immunoprecipitation
Classification Monoclonal
Clone H3.105.5; same as Ab105
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Host Species Mouse
Immunogen Extracellular domain of recombinant human c-erbB-3/HER-3 oncoprotein
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline EGFR Family
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody.

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.

Host Species: Mouse

Clone: H3.105.5; same as Ab105

Isotype: IgG1

Species Reactivity: Human and Mouse. Others not tested.

Epitope: Extracellular domain

Immunogen: Extracellular domain of recombinant human HER-3/c-erbB-3 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D

Cellular Localization: Cytoplasmic and membrane

Recommended for:

  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry
  • Inhibits Heregulin (NDF) Binding
  • Effect on Tumor Growth (Noninhibitory)

Note:

USA: RUO; Int'l: RUO