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Thermo Scientific™ Lab Vision™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS303P1ABX

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Catalog No. MS303P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen HER-3/c-erbB-3 Ab-5
Applications Immunofluorescence
Applications Immunoprecipitation
Classification Monoclonal
Clone H3.105.5; same as Ab105
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Host Species Murine
Immunogen Extracellular domain of recombinant human c-erbB-3/HER-3 oncoprotein
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline EGFR Family
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine

Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody.

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.

Host Species: Mouse

Clone: H3.105.5; same as Ab105

Isotype: IgG1

Species Reactivity: Human and Mouse. Others not tested.

Epitope: Extracellular domain

Immunogen: Extracellular domain of recombinant human HER-3/c-erbB-3 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D

Cellular Localization: Cytoplasmic and membrane

Recommended for:

  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry
  • Inhibits Heregulin (NDF) Binding
  • Effect on Tumor Growth (Noninhibitory)

Note:

USA: RUO; Int'l: RUO