Thermo Scientific™ Lab Vision™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody
Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS303P1ABX
Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-5, Mouse Monoclonal Antibody.c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.
Host Species: Mouse
Clone: H3.105.5; same as Ab105
Species Reactivity: Human and Mouse. Others not tested.
Epitope: Extracellular domain
Immunogen: Extracellular domain of recombinant human HER-3/c-erbB-3 oncoprotein
Molecular Weight: 185kDa
Positive Control: T47D
Cellular Localization: Cytoplasmic and membrane
- Western Blotting (Not suitable)
- Flow Cytometry
- Inhibits Heregulin (NDF) Binding
- Effect on Tumor Growth (Noninhibitory)
USA: RUO; Int'l: RUO
|H3.105.5; same as Ab105|
|Extracellular domain of recombinant human c-erbB-3/HER-3 oncoprotein|