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HER-3/c-erbB-3 Ab-4 Mouse Monoclonal Antibody, Epredia™
Epredia™ HER-3/c-erbB-3 Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.
Supplier: Thermo Fisher Scientific MS262B1
Description
c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.Host Species: Mouse
Clone: H3.90.6; same as Ab90
Isotype: IgG2a
Species Reactivity: Human. Others not tested.
Epitope: Extracellular domain
Immunogen: Extracellular fragment of recombinant human HER-3/c-erbB-3 oncoprotein
Molecular Weight: 185kDa
Positive Control: T47D cells
Cellular Localization: Cytoplasmic and membrane
Recommended for:
- Western Blotting (Not suitable)
- Immunofluorescence
- Immunoprecipitation
- Flow Cytometry
- Effect on Heregulin (NDF) Binding (Noninhibitory)
- Effect on Tumor Growth (Noninhibitory)
Note:
USA: RUO; Int'l: RUO
Specifications
| HER-3/c-erbB-3 Ab-4 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Oncogenesis | |
| Human | |
| IgG2a |
| Flow Cytometry, Immunofluorescence, Immunoprecipitation | |
| H3.90.6; same as Ab90 | |
| Biotin | |
| Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein | |
| RUO | |
| Primary | |
| Concentrated |