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Thermo Scientific™ Lab Vision™ HER-3/c-erbB-3 Ab-4, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-4, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS262P1ABX

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Catalog No. MS262P1ABX

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Description & Specifications

Specifications

Antigen HER-3/c-erbB-3 Ab-4
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunoprecipitation
Classification Monoclonal
Clone H3.90.6; same as Ab90
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein
Isotype IgG2a
Quantity 100µL
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ HER-3/c-erbB-3 Ab-4, Mouse Monoclonal Antibody.

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.

Host Species: Mouse

Clone: H3.90.6; same as Ab90

Isotype: IgG2a

Species Reactivity: Human. Others not tested.

Epitope: Extracellular domain

Immunogen: Extracellular fragment of recombinant human HER-3/c-erbB-3 oncoprotein

Molecular Weight: 185kDa

Positive Control: T47D cells

Cellular Localization: Cytoplasmic and membrane

Recommended for:

  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation
  • Flow Cytometry
  • Effect on Heregulin (NDF) Binding (Noninhibitory)
  • Effect on Tumor Growth (Noninhibitory)

Note:

USA: RUO; Int'l: RUO