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HER-3/c-erbB-3 Ab-2 Mouse Monoclonal Antibody, Epredia™
Epredia™ HER-3/c-erbB-3 Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.
Supplier: Thermo Fisher Scientific MS201P
Description
c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.Host Species: Mouse
Clone: 2F12
Isotype: IgG2a/κ
Species Reactivity: Human, Cow, Rat and Mouse. Others not tested.
Epitope: aa 1295-1323
Immunogen: Recombinant rat HER-3/c-erbB-3 oncoprotein
Molecular Weight: 185kDa
Positive Control: T47D cells
Cellular Localization: Cytoplasmic and membrane
Recommended for:
- Western Blotting
- Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Specifications
HER-3/c-erbB-3 Ab-2 | |
Monoclonal | |
200μg/mL | |
Mouse | |
1 mL | |
Oncogenesis | |
Bovine, Human, Mouse, Rat | |
IgG2a κ |
Immunoprecipitation, Western Blot | |
2F12 | |
Unconjugated | |
Recombinant rat c-erbB-3/HER-3 oncoprotein | |
RUO | |
Primary | |
Concentrated |