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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody


Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Thermo Scientific™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  MS325P1ABX

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Catalog No. MS325P1ABX

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Description & Specifications

Specifications

Antigen HER-2/c-erbB-2/neu Ab-8
Applications Immunoprecipitation
Classification Monoclonal
Clone e2-4001
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Formulation Ab Without BSA/Azide (Frozen)
Host Species Murine
Immunogen Cytoplasmic domain of recombinant human c-erbB-2/HER-2 oncoprotein
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine
Target Species Rat

Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Thermo Scientific™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.

c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. The c-erbB-2 protein is overexpressed in a variety of carcinomas especially those of breast and ovary.

Host Species: Mouse

Clone: e2-4001

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not tested.

Epitope: Cytoplasmic domain

Immunogen: Cytoplasmic domain of recombinant human HER-2/c-erbB-2 oncoprotein

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or T47D cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry
  • Western Blotting
  • Immunoprecipitation (Native and Denatured)

Note:

USA: RUO; Int'l: RUO