Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody
Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Thermo Scientific™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Thermo Scientific™ Lab Vision™ MS325P1ABX
Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Thermo Scientific™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. The c-erbB-2 protein is overexpressed in a variety of carcinomas especially those of breast and ovary.
Host Species: Mouse
Species Reactivity: Human, Mouse and Rat. Others not tested.
Epitope: Cytoplasmic domain
Immunogen: Cytoplasmic domain of recombinant human HER-2/c-erbB-2 oncoprotein
Molecular Weight: 185 kDa
Positive Control: SKBR-3 cells, or T47D cells, or Breast CA
Cellular Localization: Membrane
- Western Blotting
- Immunoprecipitation (Native and Denatured)
USA: RUO; Int'l: RUO
|Ab Without BSA/Azide (Frozen)|
|Cytoplasmic domain of recombinant human c-erbB-2/HER-2 oncoprotein|