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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody


Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Thermo Scientific™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  MS325P1ABX

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Catalog No. MS325P1ABX

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Description & Specifications

Specifications

Antigen HER-2/c-erbB-2/neu Ab-8
Applications Immunoprecipitation
Classification Monoclonal
Clone e2-4001
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Formulation Ab Without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Cytoplasmic domain of recombinant human c-erbB-2/HER-2 oncoprotein
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary

Recommended for Immunohistochemistry, Western Blotting and Immunoprecipitation (Native and Denatured), Thermo Scientific™ HER-2/c-erbB-2/neu Ab-8, Mouse Monoclonal Antibody provides accurate, reproducible results.

c-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. The c-erbB-2 protein is overexpressed in a variety of carcinomas especially those of breast and ovary.

Host Species: Mouse

Clone: e2-4001

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not tested.

Epitope: Cytoplasmic domain

Immunogen: Cytoplasmic domain of recombinant human HER-2/c-erbB-2 oncoprotein

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or T47D cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry
  • Western Blotting
  • Immunoprecipitation (Native and Denatured)

Note:

USA: RUO; Int'l: RUO