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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-6, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-6, Mouse Monoclonal Antibody.

$268.92 - $1,264.16

Specifications

Antigen HER-2/c-erbB-2/neu Ab-6
Clone N28
Applications Immunoprecipitation
Classification Monoclonal
Conjugate Unlabeled
View More Specs
Products
Catalog Number Mfr. No. Concentration Quantity Price Quantity    

MS307P

 
thermo scientific™ lab vision™
MS307P
200μg/mL 1mL Each for $1,194.86

MS307P0

 
thermo scientific™ lab vision™
MS307P0
200μg/mL 100μL Each for $268.92

MS307P1

 
thermo scientific™ lab vision™
MS307P1
200μg/mL 500μL Each for $752.94

MS307P1ABX

 
thermo scientific™ lab vision™
MS307P1ABX
1mg/mL 100μL Each for $831.82

MS307PABX

 
thermo scientific™ lab vision™
MS307PABX
1mg/mL 200μL Each for $1,264.16
Description & Specifications

Specifications

Antigen HER-2/c-erbB-2/neu Ab-6
Clone N28
Applications Immunoprecipitation
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Murine
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary
Immunogen Intact SKBR-3 breast cancer cells
Isotype IgG1

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-6, Mouse Monoclonal Antibody.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein.

Host Species: Mouse

Clone: N28

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells

Cellular Localization: Membrane

Recommended for:

  • Immunoprecipitation (Native and denatured)
  • Stimulates (10-fold) Tyrosine Kinase Activity
  • Effect on Tumor Growth (∽40% stimulatory)

Note:

USA: RUO; Int'l: RUO