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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

$254.61 - $1,444.02

Specifications

Antigen HER-2/c-erbB-2/neu Ab-4
Clone N12
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunofluorescence
View More Specs
Products
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity    

MS301B

 
thermo scientific™ lab vision™
MS-301-B
200�g/mL Biotin 1mL Each for $1,444.02

MS301B0

 
thermo scientific™ lab vision™
MS-301-B0
200�g/mL Biotin 100µL Each for $348.45

MS301B1

 
thermo scientific™ lab vision™
MS-301-B1
200�g/mL Biotin 500µL Each for $948.80

MS301P

 
thermo scientific™ lab vision™
MS-301-P
200�g/mL Unlabeled 1mL Each for $1,132.37

MS301P0

 
thermo scientific™ lab vision™
MS-301-P0
200�g/mL Unlabeled 100µL Each for $254.61

MS301P1

 
thermo scientific™ lab vision™
MS-301-P1
200�g/mL Unlabeled 500µL Each for $721.90

MS301P1ABX

 
thermo scientific™ lab vision™
MS301P1ABX
1mg/mL Unlabeled 100µL Each for $788.29

MS301PABX

 
thermo scientific™ lab vision™
MS-301-PABX
1mg/mL Unlabeled 200µL Each for $1,207.31
Description & Specifications

Specifications

Antigen HER-2/c-erbB-2/neu Ab-4
Clone N12
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline EGFR Family
Type Primary
Immunogen Intact SKBR-3 breast cancer cells
Isotype IgG1

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: N12

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Inhibits Tumor Growth (∽90%)
  • Inhibits Cell Proliferation
  • Effect on HER-2 Internalization (Moderate)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO