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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

$273.86 - $1,552.55

Specifications

Antigen HER-2/c-erbB-2/neu Ab-4
Clone N12
Applications Immunofluorescence,Immunohistochemistry (Frozen),Immunofluorescence,Immunohistochemistry (Frozen)
Classification Monoclonal
Cross Reactivity Human
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity  
MS301B Thermo Scientific™ Lab Vision™
MS301B
200μg/mL Biotin 1mL Each for $1,552.55
MS301B0 Thermo Scientific™ Lab Vision™
MS301B0
200μg/mL Biotin 100μL Each for $374.86
MS301B1 Thermo Scientific™ Lab Vision™
MS301B1
200μg/mL Biotin 500μL Each for $1,020.16
MS301P Thermo Scientific™ Lab Vision™
MS301P
200μg/mL Unlabeled 1mL Each for $1,217.59
MS301P0 Thermo Scientific™ Lab Vision™
MS301P0
200μg/mL Unlabeled 100μL Each for $273.86
MS301P1 Thermo Scientific™ Lab Vision™
MS301P1
200μg/mL Unlabeled 500μL Each for $776.16
MS301P1ABX Thermo Scientific™ Lab Vision™
MS301P1ABX
1mg/mL Unlabeled 100μL Each for $847.61
MS301PABX Thermo Scientific™ Lab Vision™
MS301PABX
1mg/mL Unlabeled 200μL Each for $1,298.16
Specifications

Description

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-4, Mouse Monoclonal Antibody.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: N12

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: Extracellular domain

Immunogen: Intact SKBR-3 breast cancer cells

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Immunoprecipitation (Not suitable)
  • Inhibits Tumor Growth (∽90%)
  • Inhibits Cell Proliferation
  • Effect on HER-2 Internalization (Moderate)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

HER-2/c-erbB-2/neu Ab-4
Immunofluorescence,Immunohistochemistry (Frozen),Immunofluorescence,Immunohistochemistry (Frozen)
Human
Murine
EGFR Family
Intact SKBR-3 breast cancer cells
N12
Monoclonal
Concentrated
RUO
Primary
IgG1