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HER-2/c-erbB-2/neu Ab-16 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-16, Mouse Monoclonal Antibody.

Supplier:  Thermo Fisher Scientific MS600PABX

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Catalog No. MS600PABX



Description

Description

c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: L26

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Involved in the formation of heterodimers

Immunogen: Extracellular domain of recombinant human HER-2/c-erbB-2 oncoprotein

Molecular Weight: 185kDa

Positive Control: SKBR-3 cells

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting (Not suitable)
  • Immunoprecipitation (Native only)
  • Inhibits Binding of EGF (∽70%), NDF (∽40%)
  • Reduces Affinity of EGF (3-fold) and NDF (2-fold)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

HER-2/c-erbB-2/neu Ab-16
Monoclonal
1mg/mL
Mouse
200 μL
EGFR Family
Human
IgG2a κ
Immunoprecipitation
L26
Unconjugated
Extracellular domain of recombinant human c-erbB-2/HER-2 oncoprotein
RUO
Primary
Concentrated
SDS
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