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HER-2/c-erbB-2/neu Ab-16 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ HER-2/c-erbB-2/neu Ab-16, Mouse Monoclonal Antibody.
Supplier: Thermo Fisher Scientific MS600PABX
Description
c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. Approximately 25% of primary breast and ovarian tumors were found to overexpress the proteinHost Species: Mouse
Clone: L26
Isotype: IgG1/κ
Species Reactivity: Human. Others not tested.
Epitope: Involved in the formation of heterodimers
Immunogen: Extracellular domain of recombinant human HER-2/c-erbB-2 oncoprotein
Molecular Weight: 185kDa
Positive Control: SKBR-3 cells
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Not suitable)
- Western Blotting (Not suitable)
- Immunoprecipitation (Native only)
- Inhibits Binding of EGF (∽70%), NDF (∽40%)
- Reduces Affinity of EGF (3-fold) and NDF (2-fold)
Note:
USA: RUO; Int'l: RUO
Specifications
HER-2/c-erbB-2/neu Ab-16 | |
Monoclonal | |
1mg/mL | |
Mouse | |
200 μL | |
EGFR Family | |
Human | |
IgG2a κ |
Immunoprecipitation | |
L26 | |
Unconjugated | |
Extracellular domain of recombinant human c-erbB-2/HER-2 oncoprotein | |
RUO | |
Primary | |
Concentrated |