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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-16, Mouse Monoclonal Antibody


Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-16, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS600P1ABX

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Catalog No. MS600P1ABX

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Description & Specifications

Specifications

Antigen HER-2/c-erbB-2/neu Ab-16
Applications Immunoprecipitation
Classification Monoclonal
Clone L26
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Extracellular domain of recombinant human c-erbB-2/HER-2 oncoprotein
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline EGFR Family
Type Primary

Provide accurate, reproducible results with the Thermo Scientific™ HER-2/c-erbB-2/neu Ab-16, Mouse Monoclonal Antibody.

c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Mouse

Clone: L26

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Involved in the formation of heterodimers

Immunogen: Extracellular domain of recombinant human HER-2/c-erbB-2 oncoprotein

Molecular Weight: 185kDa

Positive Control: SKBR-3 cells

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Not suitable)
  • Western Blotting (Not suitable)
  • Immunoprecipitation (Native only)
  • Inhibits Binding of EGF (∽70%), NDF (∽40%)
  • Reduces Affinity of EGF (3-fold) and NDF (2-fold)

Note:

USA: RUO; Int'l: RUO