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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody


Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation, Thermo Scientific™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  RB103P1ABX

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Catalog No. RB103P1ABX

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Description & Specifications

Specifications

Antigen HER-2/c-erbB-2/neu Ab-1
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Non-Human Primate
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen Synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein. This Sequence is identical in rat neu protein.
Isotype IgG
Quantity 500µL
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary

Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation, Thermo Scientific™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Monkey, Rat and Mouse. Others not tested.

Epitope: C-terminal

Immunogen: Synthetic peptide derived from C-terminus of human HER-2/c-erbB-2 protein. This sequence is identical in rat neu protein.

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or T47D cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO