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Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody


Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation, Thermo Scientific™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.

Manufacturer: thermo scientific™ lab vision™  RB103P1ABX

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Catalog No. RB103P1ABX

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Description & Specifications

Specifications

Antigen HER-2/c-erbB-2/neu Ab-1
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Non-Human Primate
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen Synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein. This Sequence is identical in rat neu protein.
Isotype IgG
Quantity 500μL
Regulatory Status RUO
Research Discipline Oncogenesis
Type Primary
Monoclonal or Polyclonal Polyclonal
Target Species Human
Target Species Murine
Target Species Non-human Primate

Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation, Thermo Scientific™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.

c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Monkey, Rat and Mouse. Others not tested.

Epitope: C-terminal

Immunogen: Synthetic peptide derived from C-terminus of human HER-2/c-erbB-2 protein. This sequence is identical in rat neu protein.

Molecular Weight: 185 kDa

Positive Control: SKBR-3 cells, or T47D cells, or Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO