Thermo Scientific™ Lab Vision™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody
Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation, Thermo Scientific™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.
Manufacturer: Thermo Scientific™ Lab Vision™ RB103P1ABX
Recommended for Immunohistochemistry (Formalin/paraffin), Western Blotting and Immunoprecipitation, Thermo Scientific™ HER-2/c-erbB-2/neu Ab-1, Rabbit Polyclonal Antibody provides accurate, reproducible results.c-erbB-2, second member (c-erbB-2/HER-2/neu) of the c-erbB family is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein
Host Species: Rabbit
Species Reactivity: Human, Monkey, Rat and Mouse. Others not tested.
Immunogen: Synthetic peptide derived from C-terminus of human HER-2/c-erbB-2 protein. This sequence is identical in rat neu protein.
Molecular Weight: 185 kDa
Positive Control: SKBR-3 cells, or T47D cells, or Breast CA
Cellular Localization: Membrane
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|Synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein. This Sequence is identical in rat neu protein.|