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Thermo Scientific™ Lab Vision™ HER-2/c-erB-2/neu, Rabbit Monoclonal Antibody


Recommended for Immunohistochemistry (Formalin/paraffin), Thermo Scientific™ HER-2/c-erB-2/neu, Rabbit Monoclonal Antibody is part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

Manufacturer: thermo scientific™ lab vision™  RM9103S0

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Catalog No. RM9103S0

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Description & Specifications

Specifications

Format Concentrated
Cross Reactivity Human
Host Species Rabbit
Applications Immunohistochemistry (Paraffin)
Immunogen Recombinant protein encoding extracellular domain of human HER-2
Antigen HER-2/c-erB-2/neu
Isotype IgG
Clone SP3
Regulatory Status IVD
Quantity 100µL
Conjugate Unlabeled
Research Discipline Oncogenesis
Type Primary
Classification Monoclonal

Recommended for Immunohistochemistry (Formalin/paraffin), Thermo Scientific™ HER-2/c-erB-2/neu, Rabbit Monoclonal Antibody is part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.

Host Species: Rabbit

Clone: SP3

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Extracellular domain

Immunogen: Recombinant protein encoding extracellular domain of human HER-2

Molecular Weight: 185 kDa

Positive Control: Breast CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)