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Thermo Scientific™ Lab Vision™ Heparan Sulfate Proteoglycan/Perlecan Ab-1, Rat Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments.

Manufacturer: thermo scientific™ lab vision™  RT794P1ABX

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Catalog No. RT794P1ABX

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Description & Specifications


Host Species Rat
Quantity 100µL
Clone A7L6
Format Concentrated
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Immunogen Murine EHS laminin preparation
Applications Immunohistochemistry (Frozen)
Isotype IgG2a kappa
Regulatory Status RUO
Antigen Heparan Sulfate Proteoglycan/Perlecan Ab-1
Conjugate Unlabeled
Research Discipline Angiogenesis
Classification Monoclonal
Type Primary
Concentration 1mg/mL

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Heparan Sulfate Proteoglycan/Perlecan Ab-1, Rat Monoclonal Antibody.

Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.

Host Species: Rat

Clone: A7L6

Isotype: IgG2a/κ

Species Reactivity: Human, Cow, Pig, Mouse. Others not known.

Epitope: Not determined

Immunogen: Murine EHS laminin preparation

Molecular Weight: High

Positive Control: Tonsil

Cellular Localization: Basement membrane

Recommended for:

  • Immunohistochemistry (Frozen and acid-alcohol-fixed, paraffin-embedded)
  • Western Blotting (Not verified)
  • Immunofluorescence


USA: RUO; Int'l: RUO