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Helios Armenian Hamster, FITC, Clone: 22F6, eBioscience™

Armenian Hamster Monoclonal Antibody

$201.55 - $506.05

Specifications

Antigen Helios
Clone 22F6
Host Species Armenian Hamster
Gene Alias Ikaros family zinc finger 2, IKZF2
Species Reactivity Canine, Human, Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245250

 
affymetrix
11988380
25μg Each for $201.55

50245251

 
affymetrix
11988382
100μg Each for $506.05
Description & Specifications

Specifications

Antigen Helios
Clone 22F6
Host Species Armenian Hamster
Gene Alias Ikaros family zinc finger 2, IKZF2
Species Reactivity Canine, Human, Mouse
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 22F6 monoclonal antibody reacts with human, mouse and canine Helios. Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros. It is expressed in hematopoietic stem cells in both the embryo and adult mice. While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells. Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription. Eight isoforms of Helios exist, some of which possess a dominant-negative function that has also been found to be upregulated in lymphoid malignancies, including T-acute lymphoblastic leukemia.

22F6 has been reported to cross react with rat Helios.