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Helios Armenian Hamster, APC, Clone: 22F6, eBioscience™

Armenian Hamster Monoclonal Antibody

$195.36 - $483.12

Specifications

Antigen Helios
Clone 22F6
Host Species Armenian Hamster
Gene Alias Ikaros family zinc finger 2
Species Reactivity Canine, Human, Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123236 Life Technologies
LS17988341
25 Tests Each for $195.36
501123237 Life Technologies
LS17988342
100 Tests Each for $483.12
Specifications

Description

This 22F6 monoclonal antibody reacts with human, mouse and canine Helios. Helios is a zinc-finger transcription factor first identified for its similarity to Ikaros. It is expressed in hematopoietic stem cells in both the embryo and adult mice. While the highest expression is found in regulatory T cells, Helios is not expressed in mature B cells, dendritic cells or myeloid cells. Helios can form a homodimer as well as heterodimerize with other Ikaros family members to regulate transcription. Eight isoforms of Helios exist, some of which possess a dominant-negative function that has also been found to be upregulated in lymphoid malignancies, including T-acute lymphoblastic leukemia.

22F6 has been reported to cross react with rat Helios.
Description & Specifications

Specifications

Helios
Armenian Hamster
Canine, Human, Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
22F6
Ikaros family zinc finger 2
Flow Cytometry (Intracellular Staining)
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.0075μg)/test