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Thermo Scientific™ Lab Vision™ Heat Shock Factor 1 (HSF1) Ab-1, Rat Monoclonal Antibody


Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and gel supershift experiments.

Manufacturer: thermo scientific™ lab vision™  RT405P1ABX

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Catalog No. RT405P1ABX

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Description & Specifications

Specifications

Antigen Heat Shock Factor 1 (HSF1) Ab-1
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 4B4
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Host Species Rat
Immunogen Recombinant mouse HSF1 protein (aa1-503)
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline Stress Response
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine

Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and gel supershift experiments with Thermo Scientific™ Heat Shock Factor 1 (HSF1) Ab-1, Rat Monoclonal Antibody.

HSF1 responds to cellular stress signals such as heat, heavy metals, and oxidative reagents; binds to heat shock response elements (HSEs) in the upstream region of heat shock gene and activates their transcription. Some laboratories have reported that the constitutive, non-DNA binding, monomeric form of inactive HSF1 is located in the cytoplasm. Upon activation, HSF1 is trimerized and is localized in nucleus where it binds DNA.

Host Species: Rat

Clone: 4B4

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 425-439 of mouse HSF1

Immunogen: Recombinant mouse HSF1 protein (aa 1-503)

Molecular Weight: 70-85 kDa (depending upon the source and state of cells)

Positive Control: LS174T or MAD109 cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native only)
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO