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Thermo Scientific™ Lab Vision™ Heat Shock Factor 1 (HSF1) Ab-1, Rat Monoclonal Antibody


Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and gel supershift experiments.

Manufacturer: thermo scientific™ lab vision™  RT405P1ABX

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Catalog No. RT405P1ABX

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Description & Specifications

Specifications

Antigen Heat Shock Factor 1 (HSF1) Ab-1
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 4B4
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Host Species Rat
Immunogen Recombinant mouse HSF1 protein (aa1-503)
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Stress Response
Type Primary

Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and gel supershift experiments with Thermo Scientific™ Heat Shock Factor 1 (HSF1) Ab-1, Rat Monoclonal Antibody.

HSF1 responds to cellular stress signals such as heat, heavy metals, and oxidative reagents; binds to heat shock response elements (HSEs) in the upstream region of heat shock gene and activates their transcription. Some laboratories have reported that the constitutive, non-DNA binding, monomeric form of inactive HSF1 is located in the cytoplasm. Upon activation, HSF1 is trimerized and is localized in nucleus where it binds DNA.

Host Species: Rat

Clone: 4B4

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 425-439 of mouse HSF1

Immunogen: Recombinant mouse HSF1 protein (aa 1-503)

Molecular Weight: 70-85 kDa (depending upon the source and state of cells)

Positive Control: LS174T or MAD109 cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native only)
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO