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Thermo Scientific™ Halt™ Protease and Phosphatase Inhibitor Cocktails

Prevent protein degradation and stabilize phosphorylation with this all-in-one cocktail of protease and phosphatase inhibitors.

Manufacturer: thermo scientific™  78441

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Catalog No. PI78441

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Description & Specifications


Quantity 1mL
Formulation Inhibitors stabilized in aqueous solution
Sufficient For 100mL of sample
Format Liquid
Description Halt Protease and Phosphatase Inhibitor Cocktail, EDTA-Free
Composition Sodium fluoride, Sodium orthovanadate, beta-Glycerophosphate, Sodium pyrophosphate, Aprotinin, Bestatin, E64, Leupeptin

The all-in-one Thermo Scientific™ Halt Protease and Phosphatase Inhibitor Cocktail provides the convenience of a single solution with full sample protection.

Additional Information and Online Ordering »

This broad-spectrum Halt Protease and Phosphatase Inhibitor Cocktail is specifically optimized to protect proteins from degradation during extraction and purification. The cocktail contains inhibitors against the major classes of proteases and phosphatases, targeting aminopeptidases, cysteine and serine proteases and serine/threonine and protein tyrosine phosphatases. To promote the inhibition of metalloproteases, 0.5M EDTA is provided in a separate tube. The 100X cocktails, available in regular and EDTA-free formulations and several package formats, are refrigerator-stable liquids that are very easy to use for nearly any sample or experimental scale.


  • Complete protection all-in-one cocktail contains both protease and phosphatase inhibitors

  • Multiple package sizes choose from four convenient packages sizes to match nearly any scale

  • Convenient the 100X liquid formulation is much easier and more effective to use than individual inhibitors and other formats

  • Easy storage aqueous-based format allows for convenient cold-room storage without freezing, by contrast with DMSO-based cocktails

  • Compatible can be used in mass spectrometry (MS) because it does not contain AEBSF, which can cause peaks to shift

  • Validated fully compatible with Thermo Scientific Pierce™ Cell Lysis Buffers


Formulations with and without supplementary vial of EDTA for metalloprotease inhibition, both of which are offered in four package sizes.