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Tocris™ GSK 650394

Serum- and glucocorticoid-regulated kinase (SGK) inhibitor

$252.39 - $1,050.42

Specifications

Product Type GSK 650394
Inhibitors GSK 650394
Molecular Weight 382.45
Purity >97
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

357210R

 
tocris™
357210
10mg Each for $252.39

357250R

 
tocris™
357250
50mg Each for $1,050.42
Description & Specifications

Specifications

Product Type GSK 650394
Inhibitors GSK 650394
Molecular Weight 382.45
Purity >97

Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor (IC50 values are 62 and 103nM for SGK1 and SGK2 respectively). Displays >30-fold selectivity over Akt and other related kinases. Inhibits androgen-stimulated growth of LNCaP cells, a human prostate carcinoma cell line (IC50 ∽ 1μM).

  • Chemical Name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoic acid
  • Formula: C25H22N2O2
  • CAS Number: 890842-28-1
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >97