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Granzyme M Mouse anti-Human, eFluor 660, Clone: 4B2G4, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $520.55

Specifications

Antigen Granzyme M
Clone 4B2G4
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124541

 
affymetrix
50977441
25 tests Each for $216.05

501124542

 
affymetrix
50977442
100 tests Each for $520.55
Description & Specifications

Specifications

Antigen Granzyme M
Clone 4B2G4
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate eFluor 660
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

Granzyme M is one of five granzyme serine proteases that have been indentified in humans. These proteins are expressed in the granules of NK cells and cytotoxic T cells, and are critical for the induction of target cell apoptosis through the cleavage of intracellular substrates. Although not as well characterized as some of the other family members, Granzyme M has been found to exhibit some distinct functions. These include the non-cytotoxic inhibition of cytomegalovirus replication, induction of apoptosis in tumor cells, and contribution to the TLR4-induced inflammatory process.