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Thermo Scientific™ Lab Vision™ Granzyme B Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Granzyme B Ab-1, Mouse Monoclonal Antibody.

$244.78 - $1,117.06

Specifications

Antigen Granzyme B Ab-1
Clone GZB01
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

MS1157R7

 
thermo scientific™ lab vision™
MS-1157-R7
7mL Each for $622.84

MS1157S

 
thermo scientific
MS-1157-S
1mL Each for $1,117.06

MS1157S0

 
thermo scientific
MS-1157-S0
100µL Each for $244.78

MS1157S1

 
thermo scientific™ lab vision™
MS-1157-S1
500µL Each for $745.78
Description & Specifications

Specifications

Antigen Granzyme B Ab-1
Clone GZB01
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
Host Species Mouse
Regulatory Status IVD
Research Discipline Apoptosis
Type Primary
Immunogen Recombinant protein encoding the N-terminus of the mature granzyme B

Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Granzyme B Ab-1, Mouse Monoclonal Antibody,  one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.

Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified. One of these, human granzyme B, is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. Exocytosis of granzyme-containing granules in the cytoplasm of the target cell leads to the induction of DNA fragmentation and apoptosis.

Host Species: Mouse

Clone: GZB01

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: N-terminal

Immunogen: Recombinant protein encoding the N-terminus of the mature granzyme B

Molecular Weight: 32 kDa

Positive Control: Hodgkin's lymphoma, Tonsil

Cellular Localization: Granular cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)