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Granzyme A Mouse anti-Human, eFluor 660, Clone: CB9, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $315.48

Specifications

Antigen Granzyme A
Clone CB9
Host Species Murine
Gene Alias CTLA-3, Fragmentin-1, TSP-1
Applications Flow Cytometry (Intracellular Staining)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124504 Life Technologies
LS50917741
25 Tests Each for $170.28
501124505 Life Technologies
LS50917742
100 Tests Each for $315.48
Specifications

Description

This CB9 monoclonal antibody reacts with human Granzyme A. Granzyme A is the most abundantly expressed of the granzyme serine proteases, which are proteins released from the granules of NK cells and cytotoxic T lymphocytes that induce death in target cells by cleavage of intracellular substrates. They play a critical role in immune defense against viruses, tumors, and intracellular bacteria. Granzyme A activates caspase-independent cell death pathways morphologically similar to apoptosis and characterized by mitochondrial and DNA damage. It may also play a role in inflammation, as the precursor form of IL-1 beta (pro-IL-1 beta) is among its target substrates. Granzyme A shares overlapping substrate specificity with the closely-related Granzyme K, which is believed to account for the minimal decrease in cytotoxicity of Granzyme A-deficient CTL.
Description & Specifications

Specifications

Granzyme A
Murine
Flow Cytometry (Intracellular Staining)
eFluor 660
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.06μg)/test
CB9
CTLA-3, Fragmentin-1, TSP-1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer