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Glycoprotein VI Mouse anti-Human, eFluor 660, Clone: HY101, eBioscience™

Mouse Monoclonal Antibody

$137.75 - $311.75

Specifications

Antigen Glycoprotein VI
Clone HY101
Host Species Mouse
Gene Alias GPVI, GP6
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124553

 
affymetrix
50981341
25 tests Each for $137.75

501124554

 
affymetrix
50981342
100 tests Each for $311.75
Description & Specifications

Specifications

Antigen Glycoprotein VI
Clone HY101
Host Species Mouse
Gene Alias GPVI, GP6
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 660
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The HY101 monoclonal antibody reacts with the glycoprotein VI (GPVI), a 62kDa type-I transmembrane glycoprotein that is expressed on mature megakaryotes and platelets. GPVI associates with the Fc receptor (FcR) gamma-chain to form a high affinity receptor for collagen. GPVI has also been reported to bind convulxin (Cvx). Phosphorylation of the ITAMs present on the FcR gamma-chain leads to recruitment of Src family kinases and activation of downstream signal transduction. GPVI has been reported to play a critical role in platelet activation and aggregation.