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Alfa Aesar™ Glybenzcyclamide, 99%

$122.14 - $447.22

Chemical Identifiers

CAS 10238-21-8
Molecular Formula C23H28ClN3O5S
Molecular Weight (g/mol) 494.003
MDL Number MFCD00056625
InChI Key ZNNLBTZKUZBEKO-UHFFFAOYSA-N
Synonym daonil
PubChem CID 3488
ChEBI CHEBI:5441
IUPAC Name 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
SMILES COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAB2145914 View Documents Alfa Aesar™
B2145914
25g Each for $122.14
 
AAB2145922 View Documents Alfa Aesar™
B2145922
100g Each for $447.22
 
Description

Description

Applications
Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker. This compound inhibits recombinant CFTR Cl- channels (IC50 = 20 μM).

Solubility
Soluble in ethanol (5 mg/mL), DMSO (25 mg/mL), chloroform (1:36), methanol (1:250), and DMF. Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.
Specifications

Chemical Identifiers

10238-21-8
494.003
ZNNLBTZKUZBEKO-UHFFFAOYSA-N
3488
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
C23H28ClN3O5S
MFCD00056625
daonil
CHEBI:5441
COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

Specifications

171°C to 174°C
10238-21-8
MFCD00056625
ZNNLBTZKUZBEKO-UHFFFAOYSA-N
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
3488
494.01
Glybenzcyclamide
25g
C23H28ClN3O5S
daonil
COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
494.003
CHEBI:5441
99%
Safety and Handling

Safety and Handling

Recommended Storage : 2° to 8°C