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Alfa Aesar™ Glybenzcyclamide, 99%

$117.24 - $434.54

Chemical Identifiers

Chemical Name or Material Glybenzcyclamide
CAS 10238-21-8
Molecular Formula C23H28ClN3O5S
Formula Weight 494.01g/mol
MDL Number MFCD00056625
Synonym Glibenclamide; Glyburide
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAB2145914

 
alfa aesar™
B21459-14
25g Each for $117.24

AAB2145922

 
alfa aesar™
B21459-22
100g Each for $434.54
Description & Specifications

Specifications

Melting Point 171° to 174°C
Quantity 25g
Chemical Name or Material Glybenzcyclamide
CAS 10238-21-8
Assay 99%
Molecular Formula C23H28ClN3O5S
Formula Weight 494.01g/mol
MDL Number MFCD00056625
Synonym Glibenclamide; Glyburide
Recommended Storage 2° to 8°C

Applications
Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker. This compound inhibits recombinant CFTR Cl- channels (IC50 = 20 μM).

Solubility
Soluble in ethanol (5 mg/mL), DMSO (25 mg/mL), chloroform (1:36), methanol (1:250), and DMF. Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.

Safety and Handling

2° to 8°C