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Glial Fibrillary Acid Protein (GFAP) Mouse, Alexa Fluor 488, Clone: GA5, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $404.55

Specifications

Antigen Glial Fibrillary Acid Protein (GFAP)
Clone GA5
Host Species Mouse
Species Reactivity Chicken, Human, Mouse, Pig, Rabbit, Rat
Applications Flow Cytometry (Intracellular Staining)
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016832

 
affymetrix
53989280
25μg Each for $172.55

5016833

 
affymetrix
53989282
100μg Each for $404.55
Description & Specifications

Specifications

Antigen Glial Fibrillary Acid Protein (GFAP)
Clone GA5
Host Species Mouse
Species Reactivity Chicken, Human, Mouse, Pig, Rabbit, Rat
Applications Flow Cytometry (Intracellular Staining)
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This GA5 monoclonal antibody reacts with human, mouse, rat, chicken, rabbit, and pig glial fibrillary acidic protein (GFAP). This 49kDa type III intermediate filament protein is expressed in neural tissues and distinguishes astrocytes from other glial cells during central nervous system development. Three alternative splice variants of GFAP exist; however, α-GFAP is the predominant form expressed in astrocytes. GFAP can co-assemble with vimentin and nestin in astrocytes, but such associations are not required for assembly. Like other intermediate filaments, GFAP assembly is dependent on phosphorylation and dephosphorylation of the N-terminal domain. Studies have demonstrated that mutations in the GFAP gene lead to Alexander disease. Moreover, GFAP has also been shown to be overexpressed in certain glial-derived tumors.