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GILZ Rat anti-Mouse, PE, Clone: CFMKG15, eBioscience™

Rat Monoclonal Antibody

$187.05 - $433.55

Specifications

Antigen GILZ
Clone CFMKG15
Host Species Rat
Gene Alias Glucocorticoid-Induced Leucine Zipper, TSC22D3
Species Reactivity Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010770

 
affymetrix
12403382
100μg Each for $433.55

5010769

 
affymetrix
12-4033-80
25μg Each for $187.05
Description & Specifications

Specifications

Antigen GILZ
Clone CFMKG15
Host Species Rat
Gene Alias Glucocorticoid-Induced Leucine Zipper, TSC22D3
Species Reactivity Mouse
Applications Flow Cytometry (Intracellular Staining)
Applications Immunocytochemistry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

GILZ is a leucine-zipper-containing protein that is induced by glucocorticoids. It is expressed in mast cells, monocytes, macrophages, dendritic cells, and T cells. GILZ has been shown to inhibit production of IL-2 as well as TCR-driven upregulation of FasL. GILZ mediates these changes in transcription, at least in part, by inhibiting DNA-binding of the transcription factors AP-1 and NF-κB. GILZ has also been shown to mediate anti-inflammatory signals in macrophages and dendritic cells by interfering with NF-κB-mediated signaling. Although GILZ has been reported to localize to the nucleus, more recent reports as well as testing at eBioscience have observed predominantly cytoplasmic staining.