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GILZ Rat anti-Mouse, Clone: CFMKG15, eBioscience™

Rat Monoclonal Antibody

$129.05 - $361.05

Specifications

Antigen GILZ
Clone CFMKG15
Host Species Rat
Gene Alias Glucocorticoid-Induced Leucine Zipper, TSC22D3
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013026 Life Technologies
LS14403380
25μg Each for $129.05
5013027 Life Technologies
LS14403382
100μg Each for $361.05
Specifications

Description

GILZ is a leucine-zipper-containing protein that is induced by glucocorticoids. It is expressed in mast cells, monocytes, macrophages, dendritic cells, and T cells. GILZ has been shown to inhibit production of IL-2 as well as TCR-driven upregulation of FasL. GILZ mediates these changes in transcription, at least in part, by inhibiting DNA-binding of the transcription factors AP-1 and NF-κB. GILZ has also been shown to mediate anti-inflammatory signals in macrophages and dendritic cells by interfering with NF-κB-mediated signaling. Although GILZ has been reported to localize to the nucleus, more recent reports as well as testing at eBioscience have observed predominantly cytoplasmic staining.
Description & Specifications

Specifications

GILZ
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CFMKG15
Glucocorticoid-Induced Leucine Zipper, TSC22D3
Flow Cytometry (Intracellular Staining),Immunocytochemistry,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL