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Gibco™ TPO (Thrombopoietin) Recombinant Human Protein DFS Item


Recombinant Human Thrombopoietin (TPO) is a bioactive protein intended for use in cell culture applications

Manufacturer: gibco™  PHC9514

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 Disclaimers

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Catalog No. PHC9514

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Description & Specifications

Specifications

For Use With (Application) Cell Culture; Mammalian Cell Culture; Cell Analysis; Cell Viability, Proliferation & Function; Angiogenesis; Stem Cell Research; Stem Cell Culture; Hematopoietic Stem Cell Culture
Molecular Weight 85kDa
Purification Method Gel-Purified
Purity 90%
Quantity 10μg
Source Human
Storage Requirements Store at -5° to -30°C.
Without Additives Carrier Protein
Structural Form Recombinant/Ligand
Protein Subtype TPO
Endotoxin Concentration <1 EU/mL
Gene Alias TPO, Thrombopoietin
Assays Proliferation of TF1 cells
Validated Application Cell Culture
Protein Family Growth Factors & Receptors
Expression System Mammalian
Protein Length 332 aa
Biological Activity 0.5ng/mL

TPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, which is the product of the myeloproliferative leukemia virus oncogene. Recombinant Human Thrombopoeitin (TPO) is one of the many GIBCO recombinant bioactive proteins available from Life Technologies.

  • High purity: minimal interference from other proteins or contaminants
  • High biological activity: more results with less protein
  • Proven compatibility: Gibco proteins bioassayed with Gibco media
  • High purity recombinant bioactive protein: to help ensure Gibco growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein
  • High biological activity: in-house activity testing of Recombinant Human Thrombopoeitin (TPO) includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays; specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line)

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